According to a Comic Con report at Empire Magazine, Mr. Raimi states that while he’s not exactly sure which hat he’ll wear on the third Spidey sequel, the ball has begun rolling on the project: "I don’t know if I’ll just be a producer on it but if I can work with the writer in such a way so that directing would be right for me, I don’t know. We’ve had our first meeting on Spider-Man 4 and we’re looking for the writer."
Sounds to me like Sam’s doing the "gradual bow-out" thing where he stays on as producer but goes on to direct something fresh and non-sequel-ish. (Or maybe a certain … prequel?)
Two things are certain:
1. There will be another Spider-Man movie.
2. We’ll have plenty of time to talk about it because it won’t be happening real quickly.